Vitamin B-6 (pyridoxine) is important for ordinary mind improvement and for holding the nervous system and immune process healthy.

Foodstuff resources of vitamin B-6 contain poultry, fish, potatoes, chickpeas, bananas and fortified cereals. Vitamin B-6 can also be taken as a dietary supplement, usually as an oral capsule, tablet or liquid.

People who have kidney disease or problems that reduce the compact intestine from absorbing vitamins and minerals from meals (malabsorption syndromes) are more possible to be vitamin B-6 deficient. Selected autoimmune ailments, some epilepsy remedies and alcohol dependence also can guide to vitamin B-6 deficiency. This can lead to a condition in which you you should not have more than enough nutritious crimson blood cells to carry enough oxygen to your body’s tissues (anemia), confusion, melancholy and a weakened immune process.

A vitamin B-6 deficiency is typically coupled with deficiency in other B vitamins, these as folic acid (vitamin B-9) and vitamin B-12.

The advisable each day quantity of vitamin B-6 for adults 50 and young is 1.3 milligrams. Following age 50, the advised day by day total is 1.5 milligrams for ladies and 1.7 milligrams for men.


Investigation on the use of vitamin B-6 for distinct conditions demonstrates:

  • Heart and blood vessel sickness and stroke. Scientists had formerly thought that vitamin B-6, when put together with folic acid (vitamin B-9) and vitamin B-12, may possibly avert health conditions of the coronary heart and blood vessels by reducing the stages of an amino acid in the blood (homocysteine). Nonetheless, reports demonstrate that the blend of these nutritional vitamins isn’t going to look to minimize the chance or severity of cardiovascular illness and stroke.
  • Morning illness. Vitamin B-6 may possibly minimize the severity of early morning sickness through pregnancy. If you have persistent nausea and vomiting, your pregnancy care service provider may prescribe vitamin B-6 supplements.
  • Premenstrual syndrome (PMS). There is some proof that vitamin B-6 may well lessen indications of PMS nonetheless, these studies are considered to be low high-quality.
  • Sideroblastic anemia. Vitamin B-6 is helpful at dealing with this genetic style of anemia.

Our consider

Green light: Generally safe

Commonly harmless

A nutritious and diverse diet program will deliver most individuals with more than enough vitamin B-6. On the other hand, for people with kidney ailments, malabsorption syndromes and specific other situations, a vitamin B-6 supplement may possibly be vital.

Vitamin B-6 supplements are also helpful for managing a genetic type of anemia and for stopping an adverse response to the antibiotic cycloserine (Seromycin), a prescription drug taken to deal with tuberculosis.

Safety and facet results

Consuming vitamin B-6 by meals appears to be protected, even in extreme quantities.

When applied as a nutritional supplement in acceptable doses, vitamin B-6 is probably protected.

Having said that, getting too much vitamin B-6 from health supplements can lead to:

  • A lack of muscle handle or coordination of voluntary actions (ataxia)
  • Unpleasant, disfiguring pores and skin lesions
  • Heartburn and nausea
  • Sensitivity to daylight (photosensitivity)
  • Numbness
  • Decreased capacity to feeling discomfort or extreme temperatures

Drug interactions

Test with your medical professional in advance of getting vitamin B-6 if you might be utilizing any medications. Attainable drug interactions contain:

  • Altretamine. Using vitamin B-6 with this chemotherapy drug may possibly lower its effectiveness, specially when also combined with the chemotherapy drug cisplatin.
  • Barbiturates. Using vitamin B-6 with a drug that functions as a central anxious program depressant (barbiturate) may well lessen the drug’s duration and intensity.
  • Anticonvulsants. Taking vitamin B-6 with fosphenytoin (Cerebyx, Sesquient) or phenytoin (Dilantin, Phenytek) could lessen the drug’s duration and depth.
  • Levodopa. Stay clear of getting vitamin B-6 with this drug utilised to address Parkinson’s disease. Vitamin B-6 might lower the performance of the drug.